28th ECCMID European Congress of Clinical Microbiology and Infectious Diseases, 21-24 April, Madrid – Spain

MEDINA has attended one more year ECCMID (European Congress of Clinical Microbiology and Infectious Diseases) in Madrid.

Dr. Olga Genilloud presented the Discovery of the novel glycosylated lanthipeptide MDN-0207, a new antibiotic with unprecedented chemical features and activity against relevant Gram-positive pathogens such as MRSA and Clostridium difficile. Preliminary results in collaboration with Prof Tanja Schneider from the University of Bonn suggest an unusual mode of action related with cell wall biosynthesis and a lipid II cycle interference that is being further investigated.

Mrs. Caridad Diaz discussed the latest advances in the contributions of the virulence gene PhoP to the metabolomic profiling of Mycobacterium tuberculosis and its implications in the development of the MTBVAC vaccine against tuberculosis, a research performed in collaboration with the group of Dr. Carlos Martín and Dr. J Gonzalo Asensio from the University of Zaragoza.