March 16, 2021:
A new article published by researchers at MEDINA reports the discovery a new cyclic peptide with interesting antiparasitic properties. This new natural product has been isolated from cultures of a wheat endophytic fungus, Nigrospora oryzae. It was active against Plasmodium falciparum and Trypanosoma cruzi, the causative agents of malaria and Chagas disease, respectively. The level of activity against the latter parasite was comparable to that of benznidazole, the standard drug currently in use to treat the disease.